' 
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 1 Review
8.5
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Ubiquinol
100 mg
†
Top Medical Research Studies
8
MitoQ effectively inhibits breast cancer
Redox-crippled MitoQ potently inhibits breast cancer and glioma cell proliferation: A negative control for verifying the antioxidant mechanism of MitoQ in cancer and other oxidative pathologies.
Focuses on MitoQ and cancer
We explored the effects of MitoQ, a specialized form of coenzyme Q10 that targets mitochondria, specifically in the context of breast cancer. This intriguing compound has shown promise as an antimetastatic agent, particularly in triple-negative breast cancer, which can be particularly aggressive. In our analysis, we observed that MitoQ had the ability to inhibit tumor growth and reduce tumor cell proliferation in preclinical models and various breast cancer cells.
To further investigate the underlying mechanisms of MitoQ's effectiveness, we introduced a modified version called dimethoxy MitoQ (DM-MitoQ). This alternative does not engage in redox-cycling, a process through which MitoQ would normally combat reactive oxygen species, thereby allowing us to compare its effects directly. Surprisingly, DM-MitoQ demonstrated slightly more potency in inhibiting cancer cell growth than MitoQ itself.
However, both compounds were effective in impairing mitochondrial function, which suggests that regardless of their antioxidant capabilities, the inhibition of mitochondrial energy production plays a crucial role in limiting cancer cell proliferation. Our findings indicate that MitoQ may not solely rely on its antioxidant properties to exert its effects, which could guide future research and therapeutic strategies.
In conclusion, we established that MitoQ significantly impacts breast cancer cell growth, and its analog DM-MitoQ serves as a useful tool for understanding the mechanisms involved. This work emphasizes the complexity of how targeting mitochondrial function can offer potential avenues for cancer treatment.
To further investigate the underlying mechanisms of MitoQ's effectiveness, we introduced a modified version called dimethoxy MitoQ (DM-MitoQ). This alternative does not engage in redox-cycling, a process through which MitoQ would normally combat reactive oxygen species, thereby allowing us to compare its effects directly. Surprisingly, DM-MitoQ demonstrated slightly more potency in inhibiting cancer cell growth than MitoQ itself.
However, both compounds were effective in impairing mitochondrial function, which suggests that regardless of their antioxidant capabilities, the inhibition of mitochondrial energy production plays a crucial role in limiting cancer cell proliferation. Our findings indicate that MitoQ may not solely rely on its antioxidant properties to exert its effects, which could guide future research and therapeutic strategies.
In conclusion, we established that MitoQ significantly impacts breast cancer cell growth, and its analog DM-MitoQ serves as a useful tool for understanding the mechanisms involved. This work emphasizes the complexity of how targeting mitochondrial function can offer potential avenues for cancer treatment.
Read More
Most Useful Reviews
8.8
Important during radiation
My doctor advised against Ubiquinol during my radiation treatment for breast cancer, as it could interfere with the radiation's purpose of killing unhealthy cells. I recognised the importance of this supplement in maintaining cell health and plan to take it post-radiation to support my recovery and prevent cancer recurrence.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
- All Researches
8
MitoQ effectively inhibits breast cancer
Redox-crippled MitoQ potently inhibits breast cancer and glioma cell proliferation: A negative control for verifying the antioxidant mechanism of MitoQ in cancer and other oxidative pathologies.
Focuses on MitoQ and cancer
We explored the effects of MitoQ, a specialized form of coenzyme Q10 that targets mitochondria, specifically in the context of breast cancer. This intriguing compound has shown promise as an antimetastatic agent, particularly in triple-negative breast cancer, which can be particularly aggressive. In our analysis, we observed that MitoQ had the ability to inhibit tumor growth and reduce tumor cell proliferation in preclinical models and various breast cancer cells.
To further investigate the underlying mechanisms of MitoQ's effectiveness, we introduced a modified version called dimethoxy MitoQ (DM-MitoQ). This alternative does not engage in redox-cycling, a process through which MitoQ would normally combat reactive oxygen species, thereby allowing us to compare its effects directly. Surprisingly, DM-MitoQ demonstrated slightly more potency in inhibiting cancer cell growth than MitoQ itself.
However, both compounds were effective in impairing mitochondrial function, which suggests that regardless of their antioxidant capabilities, the inhibition of mitochondrial energy production plays a crucial role in limiting cancer cell proliferation. Our findings indicate that MitoQ may not solely rely on its antioxidant properties to exert its effects, which could guide future research and therapeutic strategies.
In conclusion, we established that MitoQ significantly impacts breast cancer cell growth, and its analog DM-MitoQ serves as a useful tool for understanding the mechanisms involved. This work emphasizes the complexity of how targeting mitochondrial function can offer potential avenues for cancer treatment.
To further investigate the underlying mechanisms of MitoQ's effectiveness, we introduced a modified version called dimethoxy MitoQ (DM-MitoQ). This alternative does not engage in redox-cycling, a process through which MitoQ would normally combat reactive oxygen species, thereby allowing us to compare its effects directly. Surprisingly, DM-MitoQ demonstrated slightly more potency in inhibiting cancer cell growth than MitoQ itself.
However, both compounds were effective in impairing mitochondrial function, which suggests that regardless of their antioxidant capabilities, the inhibition of mitochondrial energy production plays a crucial role in limiting cancer cell proliferation. Our findings indicate that MitoQ may not solely rely on its antioxidant properties to exert its effects, which could guide future research and therapeutic strategies.
In conclusion, we established that MitoQ significantly impacts breast cancer cell growth, and its analog DM-MitoQ serves as a useful tool for understanding the mechanisms involved. This work emphasizes the complexity of how targeting mitochondrial function can offer potential avenues for cancer treatment.
Read More
User Reviews
USERS' SCORE
Good
Based on 1 Review
8.5
- All Reviews
- Positive Reviews
- Negative Reviews
8.8
Important during radiation
My doctor advised against Ubiquinol during my radiation treatment for breast cancer, as it could interfere with the radiation's purpose of killing unhealthy cells. I recognised the importance of this supplement in maintaining cell health and plan to take it post-radiation to support my recovery and prevent cancer recurrence.
Read More
